
Dispase is a protease which cleaves fibronectin, collagen IV, and to a lesser extent collagen I. It is found in some bacteria and can be isolated from culture filtrates of Bacillus polymyxa. It can be extracted, purified, and used in research. It can be particularly useful to separate embryonic epithelia and mesenchyme. Dispase II is specific for ...
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<enzyme> From bacillus polymyxa; dispase II is specific for leu-phe bonds ... Registry number: EC 3.4.99.- ... Synonym: bacterial neutral protease, dispase II, dispase i ... (26 Jun 1999) ...
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Trade name for a crude protease preparation used for disaggregating tissue in setting up primary cell cultures. Dispase gives less complete disaggreagtion than trypsin but survival of cells may be better.
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