A protein found on the surface of some immune system cells, including B cells and monocytes. Cells with CD80 on their surface cause T cells to make substances that help control immune responses. Also called B7-1.
Found on
http://www.cancer.gov/dictionary?expand=C
<immunology> The natural ligand for the T-cell antigen CD28 (antigens, CD28) mediating t-cell and B-cell adhesion. Cd80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes. The binding of CD80 to CD28 and ctla-4 provides a co-stimulatory signal to T-cells and leads to greatly upregulated lymphokine production. ... (12 ...
Found on
http://www.encyclo.co.uk/local/20973
Type: Term Definitions: 1. a type I transmembrane protein on activated B cells, activated monocytes, activated follicular dendritic cells, and some activated T cells; provides a costimulatory signal to T cells during antigen presentation; expressed in B lymphoblastoid cells.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=18418
No exact match found.
