
<chemical, molecular biology> Analogue of thymidine that induces point mutations because of its tendency to tautomerisation: in the enol form it pairs with G instead of A. ... It is used as a mutagen and also as a marker for DNA synthesis (the incorporation of BUdR can be recognised because the staining pattern differs: an even more sensitive...
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(= bromo-deoxyuridine; deoxynucleoside of 5-bromo-uracil) Analogue of thymidine that induces point mutations because of its tendency to tautomerization: in the enol form it pairs with G instead of A. It is used as a mutagen, and also as a marker for DNA synthesis (the incorporation of BUdR can be recognized because the staining pattern differs: an even more sensitive method uses a monoclonal antibody staining procedure.)
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