1) Address for a juárez wife 2) Andalusian title 3) Casa lady 4) Certain Spanish spouse 5) Chihuahua female 6) Chilean lady 7) Counterpart for madame 8) Dona 9) European lady 10) Flamenco dancer, often 11) Hacienda dweller 12) Half of a Spanish union 13) Iberian title 14) Isabel Allende title 15) JLO is one 1) Dama 
Se·ño'ra noun [ Spanish ] A Spanish title of courtesy given to a lady; Mrs.; Madam; also, a lady. 
[n] - a Spanish title of respect for a married woman
noun a Spanish title or form of address for a married woman; similar to the English `Mrs` or `madam`