1) Beleaguer 2) Bother 3) Cause great unhappiness for 4) Cause pain 5) Cause suffering 6) Defeat 7) Discomfit 8) Discompose 9) Disconcert 10) Distress 11) Distress greatly 12) French word used in English 13) Harass 14) Plague 15) Smite 16) To humble 17) To make low or humble 18) To overthrow 19) To strike or cast down Found on https://www.crosswordclues.com/clue/afflict
• (v. t.) To inflict some great injury or hurt upon, causing continued pain or mental distress; to trouble grievously; to torment. • (p. p. & a.) Afflicted. • (v. t.) To strike or cast down; to overthrow. • (v. t.) To make low or humble. Found on http://thinkexist.com/dictionary/meaning/afflict/
Af·flict' past participle & adjective [ Latin afflictus , past participle ] Afflicted. [ Obsolete] Becon. Found on http://www.encyclo.co.uk/webster/A/39
Af·flict' transitive verb [ imperfect & past participle Afflicted ; present participle & verbal noun Afflicting .] [ Latin afflictus , past participle of affigere to cast down, deject; ad + fligere to strike... Found on http://www.encyclo.co.uk/webster/A/39
to distress with mental or bodily pain; trouble greatly or grievously: to be afflicted with arthritis. · · to overthrow; defeat. · to humble. Found on https://www.infoplease.com/dictionary/afflict