tribulation 1. Something that causes great difficulty, affliction, or distress; such as, an ordeal: 'I have experienced the trials and tribulations of a struggling lexicographer.' 2. An experience that tests one's endurance, patience, or religious faith. 3. Etymology: from Old French tribulacion (12th century), from Late Latin tribulationem, trib... Found on http://www.wordinfo.info/words/index/info/view_unit/2178/2