Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. NCBI Reference Sequence: NG_029069.1 Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation...
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http://en.wikipedia.org/wiki/Survivin
Protein in tumour cells that blocks apoptosis, possibly by inhibiting caspases. Related to IAPs.
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http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Pronunciation: sur-vī′v′in Definitions: 1. Human gene encoding a unique IAP apoptosis inhibitor. Survivin is present in fetal tissues, but is undetectable in adult tissues. It is, however, expressed in transformed cell lines and in the most common types of human cancer (lung, colon, pancreas, prostate, breast) as well as...
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http://www.medilexicon.com/medicaldictionary.php?t=87107
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