Setastine (Loderix) is an antihistamine used to treat allergies and rhinitis. == Pharmacology == === Pharmacodynamics === Setastine acts as a highly selective H1 receptor antagonist. It has no anticholinergic, antiadrenergic, or antiserotonergic effects. === Pharmacokinetics === Setastine penetrates the blood-brain-barrier only weakly, hence, it i...