[gene] Phosphatase and tensin homolog (PTEN) is a protein that, in humans, is encoded by the PTEN gene. Mutations of this gene are a step in the development of many cancers. PTEN acts as a tumor suppressor gene through the action of its phosphatase protein product. This phosphatase is involved in the regulation of the cell cycle, preventing...
Found on
http://en.wikipedia.org/wiki/PTEN_(gene)
A protein that helps control many cell functions, including cell division and cell death. Mutations (changes) in the gene that makes PTEN are found in many types of cancer and other diseases. It is a type of tumor suppressor protein. Also called PTEN tyrosine phosphatase.
Found on
http://www.cancer.gov/dictionary?expand=P
(= phosphatase and tensin homolog deleted on chromosome ten; MMAC1/PTEN; TEP-1) A protein tyrosine phosphatase with homology to tensin, is a tumour-suppressor gene on chromosome 10q23. Somatic mutations in PTEN occur in multiple tumours, most markedly glioblastomas. Germ-line mutations in PTEN are responsible for Cowden disease (CD), a rare autosomal dominant multiple-hamartoma syndrome. Mutated in MMAC1/PTEN (multiple advanced cancers 1/phosphatase and tensin) homologue.
...
Found on
http://www.encyclo.co.uk/visitor-contributions.php
No exact match found.
