The 20S proteosome has 28 protein subunits arranged as an (a1 - a 7, b1 - b 7)2 complex in four stacked rings. The interior of the complex has the active sites. The b -type subunits are synthesized as pro-proteins and are proteolytically cleaved before assembly. Nomenclature is complex: see Table P2.
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Type: Term Pronunciation: prō′tē-ō-sōm Definitions: 1. A cluster of genes that encode components of the cell cytosolic proteolytic complex, a set of proteins thought to be involved in cellular processing and transport of peptides in the formation of the major histocompatibility complex class I molecules.
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