<molecular biology> A sequence of adenine nucleotides that get added to the 3' end of some primary transcript messenger RNA molecules in eukaryotes during post-transcriptional processing. The added tail is believed to confer stability to the molecule. ... Histone mRNA do not have poly A tail. The poly A tail is added post transcriptionally to...
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http://www.encyclo.co.uk/local/20973
Polyadenylic acid sequence of varying length found at the 3' end of most eukaryotic mRNAs. Histone mRNAs do not have poly-A tail. The poly-A tail is added post-transcriptionally to the primary transcript as part of the nuclear processing of RNA yielding hnRNAs with 60-200 adenylate residues in the tail. In the cytoplasm the poly-A tail on mRNAs is gradually reduced in length. The function of the poly-A tail is not clear but it is the basis of a useful technique for the isolation of eukaryotic mRNAs. The technique uses an affinity chromatography column with oligo(U) or oligo(dT) immobilized on a solid support. If cytoplasmic RNA is applied to such a column, poly-A-rich RNA (mRNA) will be retained.
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http://www.encyclo.co.uk/visitor-contributions.php
string of approximately 200 adenine nucleotides added to the 3’ end of a eukaryotic primary mRNA transcript to stabilize it
Found on
https://courses.lumenlearning.com/microbiology/chapter/glossary/
No exact match found.
