Type: Term Pronunciation: pen′drin Definitions: 1. A chloride-iodide transporter protein encoded by the gene responsible for Pendred syndrome, important in function of thyroid gland, kidney, and inner ear.
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Pendrin, also known as sodium-independent chloride/iodide transporter, is a protein that in humans is encoded by the SLC26A4 gene (solute carrier family 26, member 4). Pendrin is the protein which is mutated in pendred syndrome, which is an autosomal recessive disorder characterized by sensorineural hearing loss, goiter and a partial organificatio...
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