p.r.n.: Abbreviation meaning 'when necessary' (from the Latin 'pro re nata', for an occasion that has arisen, as circumstances require, as needed). One of a number of hallowed abbreviations of Latin terms that have traditionally been used in prescriptions. Some others: a.c. = before meals (from 'ante cibum', before meals) b.i.d. = twice a day (from... Found on http://www.medterms.com/script/main/art.asp?articlekey=8309