1) Harmfulness 2) Morbidity 3) Morbidness 4) Noxiousness 5) Unwholesomeness 1) Noxiousness 
noisomeness 1. The quality of being noxious. 2. A reference to being offensive to the senses and; especially, to the sense of smell: 'I couldn't stand the noisome garbage which has been there for days.' 3. Something which is highly obnoxious or objectionable.
noxiousness noun the quality of being noxious