Nibrin, also known as NBN or Nbs1, is a protein which in humans is encoded by the NBN gene. == Function == Nibrin is a protein associated with the repair of double strand breaks (DSBs) which pose serious damage to a genome. It is a 754 amino acid protein identified as a member of the NBS1/hMre11/RAD50(N/M/R, more commonly referred to as MRN) doubl...
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Protein thought to be defective in Nijmegen breakage syndrome. Has two modules found in cell cycle checkpoint proteins and a forkhead-associated domain.
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