1) Annoying 2) Bothersome 3) Disagreeable 4) Easily irritated or annoyed 5) Galling 6) Irritating 7) Pesky 8) Pestering 9) Pestiferous 10) Plaguey 11) Plaguy 12) Teasing 13) Vexatious 14) Vexing 1) Annoying 2) Bothersome 3) Disagreeable 4) Galling 5) Irking 6) Irritable 7) Irritating 8) Peevish 9) Pesky 10) Pestering 11) Pettish 12) Petulant 13) Plaguy 14) Techy 15) Testy 16) Tetchy 17) Thorny 18) Vexatious 19) Vexing 
irritable; difficult
causing irritation, vexation, or annoyance: to cope with a nettlesome situation. · easily provoked or annoyed: to become nettlesome over trivial matters.