<drug> Aziridine antibiotic isolated from Streptomyces caespitosus. Inhibits DNA synthesis by cross linking the strands. ... (18 Nov 1997) ... Found on http://www.encyclo.co.uk/local/20973
Aziridine antibiotic isolated from Streptomyces caespitosus . Inhibits DNA synthesis by cross-linking the strands and is used as an anti-neoplastic agent. Most active in late G1 and early S phase. Mitomycin-treated cells are sometimes used as feeder layers.
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