A latrotoxin is a high-molecular mass neurotoxin found in the venom of spiders of the genus Latrodectus (widow spiders). Latrotoxins are the main active components of the venom and are responsible for the symptoms of latrodectism. The following latrotoxins have been described: five insecticidal toxins, termed α, β, γ, δ and ε-latroinsectotoxi...
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(= a-latrotoxin; a-LTx) Major toxin from Latrodectus spp. (1401 residues). Causes release of neurotransmitters from all synapses. An insect-specific toxin, a -latroinsectotoxin, is also present in the venom and has substantial homology and similar mode of action to a -latrotoxin.
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