1) Dog-tired in London 2) Drained 3) Exhausted 4) Slang for worn out, exhausted 5) Tired 6) Very tired 1) Tired 
Tired, exhausted, or worn out.
drunk
Knackered is British slang for worn out, exhausted.
[adj] - (British) very tired
Worn out, rooted
drained adjective very tired
The morning after twenty pints and the curry, you'd probably feel knackered. Another way to describe it is to say you feel shagged. Basically worn out, good for nothing, tired out, knackered.
exhausted; very tired: He is really knackered after work.