Cytotoxic T lymphocytes (CTLs) can recognize and destroy cancer cells. However, there is also an inhibitory mechanism that interrupts this destruction. Ipilimumab turns off this inhibitory mechanism and allows CTLs to continue to destroy cancer cells. In addition to melanoma, ipilimumab is undergoing clinical trials for the treatment of non-small ...
Found on
http://en.wikipedia.org/wiki/Ipilimumab
A monoclonal antibody being studied in the treatment of certain types of cancer. Ipilimumab is made in the laboratory and binds to the molecule CTLA-4 on T cells (a type of white blood cell). Ipilimumab may block CTLA-4 and help the immune system kill cancer cells. Also called MDX-010.
Found on
http://www.cancer.gov/dictionary?expand=I
No exact match found.
