1) Cheerlessness 2) Dejection 3) Depression 4) Despair 5) Futility 6) Gloom 7) Ineffectiveness 8) Joylessness 9) Misery 10) Needlessness 11) Pointlessness 12) Sadness 13) Unhappiness 14) Worthlessness 1) Despair 2) Desperation 3) Helplessness 4) Impossibility 5) Misery 6) Unfeasibility 7) Uselessness 
[n] - the despair you feel when you have abandoned hope of comfort or success
noun the despair you feel when you have abandoned hope of comfort or success