Lymphocyte surface protein originally described as being an essential cofactor for HIV bound to CD4 to fuse with and enter the cell, later shown to be a chemokine receptor (CXCR4 in the case of lymphotropic virus strains, CCR5 for myelotropic strains). Since FIV will infect CD4-cells it is possible that the chemokine receptor is the original binding site and CD4 the co-receptor, rather than the converse.
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Found on
http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Pronunciation: fyū′zin Definitions: 1. A G protein-linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=35847
No exact match found.
