
Erdheim–Chester disease (also known as Erdheim–Chester syndrome or polyostotic sclerosing histiocytosis) is a rare disease characterized by the abnormal multiplication of a specific type of white blood cells called histiocytes, or tissue macrophages (technically, this disease is termed a non-Langerhans-cell histiocytosis). Usually, onset is in...
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http://en.wikipedia.org/wiki/Erdheim–Chester_disease

<radiology> Rare lipidosis, age: 50-70y, long bones invariably affected in the diaphysis and metaphysis with: patchy or diffuse increase in density, coarsened trabecular pattern, medullary sclerosis, cortical thickening ... (12 Dec 1998) ...
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http://www.encyclo.co.uk/local/20973

Type: Term Pronunciation: erd′hīm-ches′tĕr Definitions: 1. rare systemic disorder characterized by proliferation of histocytes, by symmetric sclerosis at diametaphysial portions of lower limbs, and by extraskeletal involvement. Microscopically, infiltration of affected organs by lipophages and Touton giant cells is evident. &n...
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http://www.medilexicon.com/medicaldictionary.php?t=25458
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