dysphoria, dysphoric 1. A depression or a state of feeling acutely hopeless, uncomfortable, and unhappy. 2. An emotional state characterized by anxiety, depression, or unease. 3. An exaggerated feeling of depression and unrest without apparent cause. 4. A mood of general dissatisfaction with life; unpleasantness, restlessness, anxiety, discomfor... Found on http://www.wordinfo.info/words/index/info/view_unit/1645/2