1) Blue 2) Doleful 3) Downcast 4) Forlorn 5) Hopeless 6) Low 7) Miserable 8) Rueful 9) Sad 10) Unhappy 11) Woebegone 1) Dejected 2) Down in the dumps 3) Downcast 4) Downcast, disheartened 5) Heartsick 6) Hopeless 
• (a.) Marked by despondence; given to despondence; low-spirited; as, a despondent manner; a despondent prisoner.
De·spond'ent adjective [ Latin despondens , -entis , present participle of despond...re .] Marked by despondence; given to despondence; low-spirited; as, a despondent manner; a despondent prisoner. -- 
[adj] - without or almost without hope
heartsick adjective without or almost without hope; `despondent about his failure`; `too heartsick to fight back`
feeling or showing profound hopelessness, dejection, discouragement, or gloom: despondent about failing health.
without or almost without hope without or almost without hope