
1) Dispose of the adipose part 2) Get the lard out 3) Make diet-friendly 4) Make lean 5) Make leaner 6) Make lite of things 7) Make meat leaner 8) Make more lean 9) Make ok for dieters 10) Make skim milk 11) Remove the adipose part 12) Remove the fat from 13) Remove the grease from 14) Render diet-friendly 
Found on 
https://www.crosswordclues.com/clue/defat
 verb remove the fat from
Found on 
https://www.encyclo.co.uk/local/20974
  No exact match found.