1) Alternate history comic 2) Famous fictional doctor 3) Fantasy comic 4) Memorable doctor in fiction 5) Occupational surname 6) Sinclair Lewis doctor 7) Sinclair lewis novel 8) Smith Found on https://www.crosswordclues.com/clue/arrowsmith
(from the article `American literature`) ...best as a social critic. His onslaughts against the `village virus` (Main Street [1920]), average businessmen (Babbitt [1922]), materialistic ... He followed this success with Arrowsmith (1925), a satiric study of the medical profession, with emphasis on the frustration of fine scien... Found on http://www.britannica.com/eb/a-z/a/104