Anticoagulants are medicinal substances that prevent or stop the clotting of blood. Heparin, a naturally occurring anticoagulant extracted from animal tissues, works to stop the coagulation of blood by preventing the formation of prothrombin, fibrin and thrombin. Anticoagulants are often used to treat bedridden patients who are at risk of developin... Found on http://www.spine-health.com/glossary/a/anticoagulants