androgynophilia, androgynophile, androgynophily In psychiatry, denoting sexual relationships with a man and a woman, either serially or concurrently (as in a “threesome”), by either a man or a woman.androgynophilia Bisexuality, but more specifically denoting sexual relationships with a man and a woman, either serially or concurrently (as in a “threesome”), by either a man or a woman.