1) Having a rapid onset 2) In a sharp manner 3) In a shrewd manner 4) In an acute manner 5) Keen way to be aware 6) Sharply 7) Sharply; severely 8) With intensity 9) With keen perception 10) With sharpness 11) With shrewdness 
• (adv.) In an acute manner; sharply; keenly; with nice discrimination.
A·cute'ly adverb In an acute manner; sharply; keenly; with nice discrimination. 
[adv] - in an acute manner 2. [adv] - having a rapid onset
acutely 1. Of senses and feelings: Keenly, delicately; sharply, poignantly. 2. Of the mental faculties: With ready or quick apprehension, with keen penetration, shrewdly. 3. Of things material: Sharply.
adverb having a rapid onset; `an acutely debilitating virus`