(= X-linked lymphoproliferative disease.) The X-linked lymphoproliferative disease (XLP), one of six described X-linked immunodeficiencies, stems from a mutation at Xq25 which renders males impotent to mount an effective immune response to the ubiquitous EBV. Proliferation of EBV-infected B-cells is apparently unregulated and invariably results in fatal mononucleosis, agammaglobulinemia, or malignant lymphoma. See SAP.
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Type: Abbreviation Definitions: 1. Abbreviation for X-linked lymphoproliferative disease.
See "XLPE"