VWM: Leukoencephalopathy with vanishing white matter, an inherited brain disease that occurs mainly in children. and follows a chronic progressive course with additional episodes of rapid deterioration following stress from febrile infection or minor head trauma. VWM is due to mutations in either of two genes -- in either the EIF2B5 gene on chromos... Found on http://www.medterms.com/script/main/art.asp?articlekey=19152