1) Anal 2) Antsy 3) Ill at ease 4) Jittery 5) Jumpy 6) Nervous 7) Nervy 8) On edge 9) Overstrung 10) Restive 11) Tensed up 12) Worried 1) Annoyed or angry 2) Antsy 3) Atlantic Records soundtrack 4) Being in a tense state 5) Edgy 6) High-strung 7) Highly strung 8) In suspense 9) Jittery 10) Jumpy 11) Nervously tense or angry 12) Nervy 13) Overstrung 14) Restive 15) Rigidly conventional 16) Tense 
Uptight is slang for tense, repressed, humourless.
tense, nervous, or jittery. · annoyed or angry. · stiffly conventional in manner or attitudes.