Semaphorins are a class of secreted and membrane proteins that act as axonal growth cone guidance molecules. They primarily act as short-range inhibitory signals and signal through multimeric receptor complexes. They are usually cues to deflect axons from inappropriate regions, especially important in neural system development. The major class of ...
Found on
http://en.wikipedia.org/wiki/Semaphorin
Type: Term Pronunciation: sem-a-fōr′in Definitions: 1. A family of membrane proteins including S-I, S-II, S-III, S-III/D and collapsing 1 that guide growth cones of axons by selective repulsion.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=80813
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