Progerin definitions

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Progerin

Progerin logo #10101) Aging-related protein
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Progerin

Progerin logo #21000 Progerin is a truncated version of lamin A protein involved in Hutchinson-Gilford progeria syndrome. Progerin is most often generated by a silent point mutation (C1824T) in the lamin A gene, LMNA. This mutation activates a cryptic splice site and gives rise to a form of lamin A with a deletion of 50 amino acids near the C-terminus. Approximately 8...
Found on http://en.wikipedia.org/wiki/Progerin
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