(= peroxisome proliferator-activated receptors) PPAR a stimulates b -oxidative degradation of fatty acids, PPAR g promotes lipid storage by regulating adipocyte differentiation. Are implicated in metabolic disorders predisposing to atherosclerosis and inflammation. PPAR a -deficient mice show prolonged response to inflammatory stimuli. PPAR a is activated by gemfibrozil and other fibrate drugs.
...Found on http://www.encyclo.co.uk/visitor-contributions.php
Peroxisome proliferator-activated receptorFound on https://sis.nlm.nih.gov/enviro/iupacglossary/annex1.html
PPAR: Abbreviation for peroxisome proliferator-activated receptor. There are 3 known subtypes of PPARs -- PPAR-alpha, PPAR-delta, and PPAR-gamma. The PPARs are members of the nuclear hormone receptor subfamily of transcription factors. The gene for PPAR-gamma is in chromosome band 3p25. It regulates the development of adipocytes (fat cells). PPAR-g...Found on http://www.medterms.com/script/main/art.asp?articlekey=15502
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