Nuclear factor of activated T-cells (NFAT) is a general name applied to a family of transcription factors shown to be important in immune response. One or more members of the NFAT family is expressed in most cells of the immune system. NFAT is also involved in the development of cardiac, skeletal muscle, and nervous systems. The NFAT transcription...
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http://en.wikipedia.org/wiki/NFAT
(= nuclear factor of activated T-cells) Transcription factor involved in regulation of IL-2 and IL-4 gene transcription (in concert with other transcription factors). NFAT is cytoplasmic until dephosphorylated by calcineurin, a step that is inhibited by cyclosporin and FK506, then translocates to the nucleus.
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http://www.encyclo.co.uk/visitor-contributions.php
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