Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene. == Function == Mesothelin is a 40 kDa protein present on normal mesothelial cells and overexpressed in several human tumors, including mesothelioma and ovarian and pancreatic adenocarcinoma. The protein was first identified by its reactivity with monoclonal anti...
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http://en.wikipedia.org/wiki/Mesothelin
A protein found on the surface of certain types of normal cells and cancer cells. Mesothelin may help these cells stick together and send signals. A higher-than-normal amount of mesothelin is found on some cancer cells, including mesothelioma, pancreatic cancer, and ovarian cancer.
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http://www.cancer.gov/dictionary?expand=M
Mesothelin: A protein attached to the cell surface that is thought to have a role in cell-adhesion and possibly in cell-to-cell recognition and signalling. Mesothelin is so named because it is made by mesothelial cells. A monoclonal antibody, which recognises mesothelin, binds to the surface of cells from mesotheliomas and some other tumors but not...
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http://www.medterms.com/script/main/art.asp?articlekey=25335
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