Myristoylated alanine-rich C-kinase substrate is a protein that in humans is encoded by the MARCKS gene. It plays important roles in cell shape, cell motility, secretion, transmembrane transport, and regulation of the cell cycle. Recently, MARCKS has been implicated in the exocytosis of a number of vesicles and granules such as mucin and chromaffi...
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http://en.wikipedia.org/wiki/MARCKS
(= myristoylated alanine-rich protein kinase C-substrate) Membrane associated (through the myristoyl residue) calmodulin- and actin-binding protein that cycles between membrane and cytoplasm depending on its phosphorylation state and on the presence of calcium/calmodulin. As a result of phosphorylation by protein kinase C, MARCKS is displaced from the membrane; dephosphorylation leads to reassociation. Implicated in macrophage activation, neurosecretion and growth-factor dependent mitogenesis.
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http://www.encyclo.co.uk/visitor-contributions.php
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