The isoprostanes are prostaglandin-like compounds formed in vivo from the free radical-catalyzed peroxidation of essential fatty acids (primarily arachidonic acid) without the direct action of cyclooxygenase (COX) enzymes. The compounds were discovered in 1990 by L. Jackson Roberts and Jason D. Morrow in the Division of Clinical Pharmacology at Va...
Found on
http://en.wikipedia.org/wiki/Isoprostane
Type: Term Pronunciation: ī-sō-pros-tān Definitions: 1. Compound derived from the free radical oxidation of arachidonic acid; resembles in some manner the prostoglandins. Elevated levels may be associated with atherosclerosis, hepatorenal syndrome, rheumatoid arthritis, and carcinogenesis.
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http://www.medilexicon.com/medicaldictionary.php?t=45958
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