(= 5-HPETE; 5-hydroperoxy-eicosatetraenoic acid) Intermediate in leukotriene synthesis. Generated from arachidonic acid by 5-lipoxygenase; the starting point for the formation of 5-HETE or of leukotriene A4 . Other related enzymes add the hydroperoxy group in different positions.
Type: Term Pronunciation: āch′pēt Definitions: 1. Abbreviation for hydroperoxyeicosatetraenoic acid.
Hydroxyeicosatetraenoic acid