1) Annoys greatly 2) Causes irritation 3) Causes vexation 4) Greatly irritates 5) Has a lot of nerve 6) Irritates 7) Irritates greatly 8) Irritates or exasperates 9) Really irritates 10) Really ticks off 11) Turns the stomach 12) Vexes Found on https://www.crosswordclues.com/clue/galls