Ficolins (Fi+Col+Lin) are a group of oligomeric lectins with subunits consisting of both collagen (Col)-like long thin stretches and fibrinogen (Fi)-like globular domains with lectin (Lin) activity usually specific for N-acetylglucosamine (GlcNAc). Like collectins (Col+lectin) such as mannan-binding lectin, ficolins are secreted, lectin-type patte...
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Type: Term Pronunciation: fi′kō-lin Definitions: 1. A protein that structurally resembles mannose-binding lectin (MBL). The polypeptide chains have a N-terminal region, a collagenlike domain, and a globular region, which is fibrinogenlike. Although H-ficolin and L-ficolin are plasma proteins generated in the liver, M-ficolin is produced ...
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