Type: Term Pronunciation: ē-kī-nō-kan′din Definitions: 1. A class of antifungal compounds targeting the fungal cell wall. Action is by specific and noncompetitive inhibition of the (1,3)-β-d-glucan synthase enzyme complex that forms glucan polymers; a major component of the fungal cell wall in several pathogenic fungi. &nb...
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Echinocandins are antifungal drugs that inhibit the synthesis of glucan in the cell wall, via noncompetitive inhibition of the enzyme 1,3-╬▓ glucan synthase and are thus called{By whom|date=May 2013} penicillin of antifungals (a property shared with papulacandins) as penicillin has a similar mechanism against bacteria but not fungi. Beta glucans a...
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