(epidermal growth factor receptor) Proteins on the surface of cells. When there are higher than normal levels (known as over expression) on cancer cells, they stimulate growth.
Found on
http://www.breastcancercare.org.uk/breast-cancer-information/glossary
The protein found on the surface of some cells and to which epidermal growth factor binds, causing the cells to divide. It is found at abnormally high levels on the surface of many types of cancer cells, so these cells may divide excessively in the presence of epidermal growth factor. Also called epidermal growth factor receptor, ErbB1, and HER1.
Found on
http://www.cancer.gov/dictionary?expand=E
Type: Abbreviation Definitions: 1. Abbreviation for epidermal growth factor receptor .
Found on
http://www.medilexicon.com/medicaldictionary.php?t=28090
EGFR: Epidermal growth factor receptor. A protein found on the surface of cells to which epidermal growth factor (EGF) binds. When EGF attaches to EGFR, it activates the enzyme tyrosine kinase, triggering reactions that cause the cells to grow and multiply. EGFR is found at abnormally high levels on the surface of many types of cancer cells, which ...
Found on
http://www.medterms.com/script/main/art.asp?articlekey=32387
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