Calnexin (CNX) is a 67kDa integral protein (that appears variously as a 90kDa, 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail...
Found on
http://en.wikipedia.org/wiki/Calnexin
Calcium-binding lectin-like protein (67 kD, 592 residues) of endoplasmic reticulum that couples glycosylation of newly synthesized proteins with their folding. Calnexin and calreticulin act together as chaperones for newly synthesized proteins and prevent ubiquitinylation and proteosomal degradation. Can be phosphorylated by Casein Kinase II.
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http://www.encyclo.co.uk/visitor-contributions.php
No exact match found.
