Integral membrane glycoprotein of the immunoglobulin superfamily (59 kD) of mammary secretory epithelium. Secreted in association with milk-fat globule membrane. The extracellular domain of butyrophilin has features that suggest it may have a receptor function.
Butyrophilin is a family of proteins. Butyrophilin (Btn) genes constitute a subgroup of at least 10 genes in the Ig superfamily identified in human, mouse, cow, goat and other species. The eponymous Btn gene (BTN1A1 in humans; Btn1a1 in mouse) is highly expressed in the secretory epithelium of the mammary gland during lactation. Other homologues a...Found on http://en.wikipedia.org/wiki/Butyrophilin
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