BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N`,N`-tetraacetic acid) is a calcium-specific aminopolycarboxylic acid. The presence of four carboxylic acid functional groups makes possible the binding of two calcium ions. The extensive flexibility of the carboxylate ligands is critical to the coordination of calcium and other metal ions. There is a ra.....
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(= 1,2-bis(o-aminophenoxy)ethane tetraacetate) Calcium chelator with low affinity for magnesium. Absorption maximum shifts when calcium is bound so it can be used as an indicator of intracellular calcium concentration (though it will chelate calcium and therefore alter the situation. See MAPTAM.
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