
1) Former papal seat 2) City in France 3) Great Schism hotspot 4) Where Frenchmen in van go 5) Whither the papacy in 1309
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https://www.crosswordclues.com/clue/avignon

Avignon (a.viˈɲɔ̃ is a French commune in south-eastern France in the department of Vaucluse on the left bank of the Rhône river. Of the 90,194 inhabitants of the city (as of 2011), about 12,000 live in the ancient town centre enclosed by its medieval ramparts. Between 1309 and 1377 during the Avignon Papacy, seven successive popes resided in ...
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http://en.wikipedia.org/wiki/Avignon

city, capital of Vaucluse département, Provence-Alpes-Côte d`Azur région, southeastern France. It lies at a point on the east bank of the Rhône River ... [3 related articles]
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http://www.britannica.com/eb/a-z/a/130
noun a town in southeastern France on the Rhone River; the seat of the papacy from 1309 to 1378 and the residence of antipopes during the Great Schism
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https://www.encyclo.co.uk/local/20974

City in Provence, France, administrative centre of Vaucluse
département, on the River Rhône, 80 km/50 mi northwest of Marseille; population (2002 est) 86,600. Tourism and food processing are important; other industries include the manufacture of leather, texti...
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https://www.encyclo.co.uk/local/21221

a city in and the capital of Vaucluse, in SE France, on the Rhone River: papal residence 1309–77. 93,024.
Found on
https://www.infoplease.com/dictionary/avignon
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