
1) Apennines religious center 2) Birthplace of a saint 3) Birthplace of multiple saints 4) Birthplace of saint francis 5) Celebrated town near Perugia 6) Commune near perugia 7) Famed Perugian town 8) Famous town in Italy 9) Franciscan home 10) Franciscan locale 11) Giotto painted here 12) Hilltown in Umbria
Found on
https://www.crosswordclues.com/clue/assisi

town, Perugia province, Umbria region, central Italy. The town lies 12 miles (19 km) east of Perugia and is famous as the birthplace of St. Francis, ... [2 related articles]
Found on
http://www.britannica.com/eb/a-z/a/114

Medieval town in Umbria, Italy, 19 km/12 mi southeast of Perugia, in the foothills of the Apennines overlooking the Tiber Valley; population (2001) 25,300. It is a long-established place of pilgrimage. St Francis was born here and is buried in the Franciscan monastery, completed in 1253. Its basilica was adorned with frescoes by Giotto,...
Found on
https://www.encyclo.co.uk/local/21221

a town in E Umbria, in central Italy: birthplace of St. Francis of Assisi. 24,002.
Found on
https://www.infoplease.com/dictionary/assisi
No exact match found.